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Societal health and economic burden of cardiovascular diseases in the population with type 2 diabetes in Qatar. A 10-year forecasting model
(
Wiley-Blackwell
, 2023 , Article)
Aims: To predict the future health and economic burden of cardiovascular disease (CVD) in type 2 diabetes (T2D) in Qatar. Materials and Methods: A dynamic multistate model was designed to simulate the progression of fatal ...
Serum immune mediators as novel predictors of response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patients with high tissue-PD-L1 expression
(
Frontiers Media S.A.
, 2023 , Article)
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related morbidity and mortality worldwide. Immune checkpoint inhibitors (ICIs) including anti-PD-1 and anti-PD-L1 antibodies, have significantly changed the ...
Role of HMGB1 and its associated signaling pathways in human malignancies
(
Elsevier
, 2023 , Article)
The High-Mobility Group Box-1 (HMGB1), a non-histone chromatin-associated protein, plays a crucial role in cancer growth and response to therapy as it retains a pivotal role in promoting both cell death and survival. HMGB1 ...
The effect of novel nitrogen-based chalcone analogs on colorectal cancer cells: Insight into the molecular pathways
(
Elsevier
, 2024 , Article)
In colorectal cancer (CRC), aberrations in KRAS are associated with aggressive tumorigenesis and an overall low survival rate because of chemoresistance and adverse effects. Ergo, complementary, and integrative medicines ...
Cultural Competence among Healthcare Professional Educators: A Mixed-Methods Study
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
As cultural diversity gains global prominence, healthcare professional educators (HPEs) are expected to exhibit a high level of cultural competence in education. Responding to this necessity requires the establishment of ...
Proteomic insight towards key modulating proteins regulated by the aryl hydrocarbon receptor involved in ovarian carcinogenesis and chemoresistance
(
Elsevier
, 2024 , Article)
Gynecological malignancies pose a severe threat to female lives. Ovarian cancer (OC), the most lethal gynecological malignancy, is clinically presented with chemoresistance and a higher relapse rate. Several studies have ...
Portrayal of Autism Spectrum disorder and its treatments in Qatar's leading newspapers: A content analysis study
(
Elsevier
, 2024 , Article)
BackgroundThe public cultivates thoughts, perceptions, and beliefs through media. Research has revealed that the media has a significant contribution to the publics’ negative perceptions and stigma surrounding Autism ...
Efficacy and safety of selinexor for patients with relapsed and refractory multiple myeloma: A meta-analysis
(
Elsevier
, 2024 , Article)
PurposeSelinexor is a first-in-class, oral selective-inhibitor-of-nuclear-export, granted accelerated approval by FDA (2019) for relapsed and refractory multiple myeloma (RRMM). We sought to quantitatively summarize the ...