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CD56 expression in breast cancer induces sensitivity to natural killer-mediated cytotoxicity by enhancing the formation of cytotoxic immunological synapse
(
Nature Publishing Group
, 2019 , Article)
We examined the potential value of the natural killer (NK) cell line; NK-92, as immunotherapy tool for breast cancer (BC) treatment and searched for biomarker(s) of sensitivity to NK-92-mediated cytotoxicity. The cytotoxic ...
Circulating microparticles as biomarkers of stroke: A focus on the value of endothelial- and platelet-derived microparticles.
(
Wiley
, 2019 , Article)
Stroke is one of the leading causes of mortality and disability worldwide. Numerous pathophysiological mechanisms involving blood vessels, coagulation and inflammation contribute to the vascular occlusion. Perturbations ...
Development of injectable PEGylated liposome encapsulating disulfiram for colorectal cancer treatment
(
MDPI AG
, 2019 , Article)
Disulfiram (DS), an anti-alcoholism medicine, shows strong anti-cancer activity in the laboratory, but the application in clinics for anti-cancer therapy has been limited by its prompt metabolism. Conventional liposomes ...
Ibrutinib-associated sever skin toxicity: A case of multiple inflamed skin lesions and cellulitis in a 68-year-old male patient with relapsed chronic lymphocytic leukemia Case report and literature review
(
SAGE Publications Ltd
, 2019 , Article)
Introduction: Ibrutinib is an oral inhibitor of Bruton's tyrosine kinase that is used for a variety of B cell hematological malignancies. Skin and subcutaneous tissue manifestations have been reported and were witnessed ...
Preemptive Dose Adjustment Effect on the Quality of Anticoagulation Management in Warfarin Patients With Drug Interactions: A Retrospective Cohort Study
(
SAGE Publications Inc.
, 2019 , Article)
One strategy to manage patients on warfarin starting an interacting drug is to increase the frequency of monitoring. Another strategy is to adjust warfarin dose around the time patient is started on an interacting medication, ...
Valproic acid induced pancreatitis in an Arab Male
(
Wolters Kluwer Medknow Publications
, 2019 , Article)
Valproate, a commonly used antiepileptic, is known to cause pancreatitis, which may present days to years after initiation of therapy. A 20-year-old Arab male patient with electroencephalogram (EEG) confirmed epileptiform ...
Relationships between physicians' characteristics and practice-setting factors and their attitude towards drug promotion
(
Blackwell Publishing Ltd
, 2019 , Article)
Purpose
This study aims to investigate relationship between attitude and belief of physicians towards drug promotion and their characteristics and practice-setting factors in Sana'a, Yemen.
Methods
A survey method ...
Workshop on proposal writing on research for health care professionals: A brief report
(
Dove Medical Press Ltd.
, 2019 , Article)
A one-day workshop on proposal writing for research for health care professionals was organized by Hospital Research Board (HRB), Nepal Cancer Hospital and Research Center Pvt. Ltd, Harisiddhi, Lalitpur, Nepal on 2nd March ...
Precise fabrication of porous one-dimensional gC3N4 nanotubes doped with Pd and Cu atoms for efficient CO oxidation and CO2 reduction
(
Elsevier B.V.
, 2019 , Article)
Rational design of graphitic carbon nitride nanostructures (gC3N4) is vital for various catalytic applications. Herein, we synthesized porous gC3N4 nanotubes (gC3N4NTs) doped with Pd and Cu (Pd/Cu/gC3N4NTs) via the consecutive ...
Perceptions and expectations of health care providers towards clinical pharmacy services in a mental health hospital in Qatar
(
Elsevier B.V.
, 2019 , Article)
Background: With the growing burden of mental disorders, pharmacists are ideally positioned to play an important role in supporting people with a mental illness. However, the value of clinical pharmacists within mental ...