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AuthorAl Moustafa, Ala-Eddin
AuthorMfoumou, Etienne
AuthorRoman, Dacian E.
AuthorNerguizian, Vahe
AuthorAlazzam, Anas
AuthorStiharu, Ion
AuthorYasmeen, Amber
Available date2016-11-01T09:25:37Z
Publication Date2016-01-21
Publication NameInternational Journal of Nanomedicineen_US
Identifierhttps://dx.doi.org/10.2147/IJN.S96361
CitationAl Moustafa A-E, Mfoumou E, Roman DE, et al. Impact of single-walled carbon nanotubes on the embryo: a brief review. International Journal of Nanomedicine. 2016;11:349-355.
ISSN1176-9114
URIhttp://hdl.handle.net/10576/4946
URIhttps://dx.doi.org/10.2147/IJN.S96361
AbstractCarbon nanotubes (CNTs) are considered one of the most interesting materials in the 21st century due to their unique physiochemical characteristics and applicability to various industrial products and medical applications. However, in the last few years, questions have been raised regarding the potential toxicity of CNTs to humans and the environment; it is believed that the physiochemical characteristics of these materials are key determinants of CNT interaction with living cells and hence determine their toxicity in humans and other organisms as well as their embryos. Thus, several recent studies, including ours, pointed out that CNTs have cytotoxic effects on human and animal cells, which occur via the alteration of key regulator genes of cell proliferation, apoptosis, survival, cell–cell adhesion, and angiogenesis. Meanwhile, few investigations revealed that CNTs could also be harmful to the normal development of the embryo. In this review, we will discuss the toxic role of single-walled CNTs in the embryo, which was recently explored by several groups including ours.
Sponsorthe Canadian Institutes for Health Research, the Cancer Research Society Inc. of Canada, the National Colorectal Cancer Campaign, the Fonds de la Recherche en Santé du Québec (FRSQ-Réseau du Cancer), and by the College of Medicine at Qatar University.
Languageen
PublisherDove Press
Subjectsingle-walled carbon nanotubes
Subjectembryo
Subjecttoxicity
TitleImpact of single-walled carbon nanotubes on the embryo: a brief review
TypeArticle
Pagination349-355
Volume Number11
ESSN1178-2013


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