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Now showing items 71-80 of 99
A novel in ovo model to study cancer metastasis using chicken embryos and GFP expressing cancer cells.
(
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
, 2019 , Article)
Cancer metastasis is the leading cause of cancer-related mortality worldwide. To date, several in vitro methodologies have been developed to understand the mechanisms of cancer metastasis and to screen various therapeutic ...
Acquisition of invasiveness by breast adenocarcinoma cells engages established hallmarks and novel regulatory mechanisms
(
International Institute of Anticancer Research
, 2019 , Article)
Background/Aim: Proteomics of invasiveness opens a window on the complexity of the metastasis-engaged mechanisms. The extend and types of this complexity require elucidation. Materials and Methods: Proteomics, immuno ...
It is all about patients' stories: Case-based learning in residents' education
(
Hamad Medical Corporation
, 2019 , Article)
Background: Problem-based learning (PBL) is an inquiry-based learning strategy which is learner centered and facilitates group discussion and critical thinking. Case-based learning (CBL), which is a more guided approach ...
Prenatal alcohol exposure is associated with early motor, but not language development in a South African cohort
(
Cambridge University Press
, 2019 , Article)
Objective:To investigate the association of prenatal alcohol exposure (PAE) and early neurodevelopment in the first 2 years of life, adjusting for maternal sociodemographic and psychosocial factors, in the Drakenstein Child ...
Proteomics of transforming growth factor ?1 (TGF ?1) signaling in 184A1 human breast epithelial cells suggests the involvement of casein kinase 2? in TGF ?1-dependent p53 phosphorylation at Ser392
(
Morion LLC
, 2019 , Article)
Aim: Transforming growth factor ?1 (TGF ?1) is a potent regulator of breast tumorigenesis. It inhibits proliferation of carcinoma cells, but the strength of its inhibitory action varies for cells from benigh, non-metastatic ...
Primary vs Revisional Gastric Bypass for Weight Loss and Improvements in Comorbidities: Comparisons at Mid-term Follow-up
(
Springer
, 2019 , Article)
Background: Revisional gastric bypass (R-RYGB) surgery is utilized for the management of inadequate weight loss or weight regain observed after some cases of bariatric surgeries. Data on the mid-term effectiveness of primary ...
Novel biomarkers for potential risk stratification of drug induced liver injury (DILI): A narrative perspective on current trends
(
Lippincott Williams and Wilkins
, 2019 , Article)
Background:Drug induced liver injury (DILI) is an increasing cause of acute liver injury especially with increasing need for pharmacotherapy of widening comorbidities amongst our ever-aging population. Uncertainty however ...
Improved liquid phase separation processes for generating biodegradable microspheres loaded with high concentrations of drugs for tumor embolization
(
Taylor and Francis Inc.
, 2019 , Article)
Drug-eluting microspheres are the most commonly used particulate embolic agents for transarterial chemoembolization of liver tumors. However, drug loading of degradable embolic particles is often insufficient. In the current ...
Ang-(1-7)/ MAS1 receptor axis inhibits allergic airway inflammation via blockade of Src-mediated EGFR transactivation in a murine model of asthma
(
Public Library of Science
, 2019 , Article)
The angiotensin-(1–7) [Ang-(1–7)]/MAS1 receptor signaling axis is a key endogenous anti-inflammatory signaling pathway. However, the mechanisms by which its mediates the anti-inflammatory effects are not completely understood. ...
In honour of Professor Patrick Couvreur, recipient of the Journal Of Drug Targeting?s Lifetime Achievement Award For 2019
(
Taylor and Francis Ltd
, 2019 , Article)
[No abstract available]